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Article

Anti-tumor effects of Mfn2 in gastric cancer.

International journal of molecular sciences - 24 Jun 2013

Zhang Ge-Er, Jin Hai-Long, Lin Xian-Ke, Chen Chao, Liu Xiao-Sun, Zhang Qing, Yu Ji-Ren

Abstract excerpt

Mitofusin-2 (Mfn2) is a mitochondrial outer membrane protein involved in mitochondrial fusion. Its mutation can cause Charcot-Marie-Tooth disease. Recent studies of Mfn2 in cancer research have not included gastric cancer. We confirmed that Mfn2 expression was lower in tumor tissue than in normal gastric mucosal tissue and that it was negatively correlated with tumor size, indicating an anti-tumor role for Mfn2....

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Identifiers

PMID: 23797661
DOI: 10.3390/ijms140713005
PMCID: PMC3742171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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