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Article

Coding variants at hexa-allelic amino acid 13 of HLA-DRB1 explain independent SNP associations with follicular lymphoma risk.

American journal of human genetics - 11 Jul 2013

Foo Jia Nee, Smedby Karin E, Akers Nicholas K, Berglund Mattias, Irwan Ishak D, Jia Xiaoming, Li Yi, Conde Lucia, Darabi Hatef, Bracci Paige M, Melbye Mads, Adami Hans-Olov, Glimelius Bengt, Khor Chiea Chuen, Hjalgrim Henrik, Padyukov Leonid, Humphreys Keith, Enblad Gunilla, Skibola Christine F, de Bakker Paul I W, Liu Jianjun

Abstract excerpt

Non-Hodgkin lymphoma represents a diverse group of blood malignancies, of which follicular lymphoma (FL) is a common subtype. Previous genome-wide association studies (GWASs) have identified in the human leukocyte antigen (HLA) class II region multiple independent SNPs that are significantly associated with FL risk. To dissect these signals and determine whether coding variants in HLA genes are responsible for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23791106
DOI: 10.1016/j.ajhg.2013.05.020
PMCID: PMC3710749

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