Parsing Good Versus Bad Signaling Pathways in the Heart

Abstract excerpt

Nine years ago, we published an article that suggested a specialized role for calcineurin–nuclear factor of activated T-cells (NFAT) signaling in regulating pathological cardiac hypertrophy preferentially over physiological growth and, in fact, the later response was associated with reduced calcineurin-NFAT activity. Since this time we and others have continued to uncover how this signaling effector pathway...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cardiac Fibrosis and Remodeling
• Share to Cardiac Structural Anomalies and Repair
• Share to Signaling Pathways in Disease