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Article

Implications of segment mismatch for influenza A virus evolution.

The Journal of general virology - 1 Jan 2018

White Maria C, Lowen Anice C

Abstract excerpt

Influenza A virus (IAV) is an RNA virus with a segmented genome. These viral properties allow for the rapid evolution of IAV under selective pressure, due to mutation occurring from error-prone replication and the exchange of gene segments within a co-infected cell, termed reassortment. Both mutation and reassortment give rise to genetic diversity, but constraints shape their impact on viral evolution: just as...

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Identifiers

PMID: 29244017
DOI: 10.1099/jgv.0.000989
PMCID: PMC5882089

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