Article
Functional CLOCK gene rs1554483 G/C polymorphism is associated with susceptibility to Alzheimer's disease in the Chinese population.
The Journal of international medical research - 1 Apr 2013
Chen Qian, Huang Chang-Quan, Hu Xiu-Ying, Li Song-Bing, Zhang Xue-Mei
Abstract excerpt
OBJECTIVE: To examine the association between the circadian locomotor output cycles kaput (CLOCK) gene rs1554483 G/C polymorphism and susceptibility to Alzheimer's disease in Chinese people. METHODS: This case-control study determined apolipoprotein E (APOE) and CLOCK rs1554483 G/C genotypes using polymerase chain reaction restriction fragment length polymorphism. RESULTS: Unrelated patients with Alzheimer's...
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