Article
Parkinson’s disease is associated with altered expression of CaV1 channels and calcium-binding proteins
14 Jun 2013
Abstract excerpt
In Parkinson's disease oxidative stress and calcium-induced excitotoxicity have been considered important mechanisms leading to cell death for decades, but the factors that make some neurons vulnerable to neurodegeneration while others remain resistant are not fully understood. Studies of the disorder in animal models suggest that the voltage-gated calcium channel subtype Ca(V)1.3 has a role in making neurons...
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