Article
Heterogeneity and immunophenotypic plasticity of malignant cells in human liposarcomas.
Stem cell research - 1 Sept 2013
Zhang Yan, Young Eric D, Bill Katelynn, Belousov Roman, Peng Tingsheng, Lazar Alexander J, Pollock Raphael E, Simmons Paul J, Lev Dina, Kolonin Mikhail G
Abstract excerpt
Liposarcomas are tumors arising in white adipose tissue (WAT) with avidity for local recurrence. Aggressive dedifferentiated liposarcomas (DDLS) may arise from well-differentiated subtypes (WDLS) upon disease progression, however, this key issue is unresolved due in large part to knowledge gaps about liposarcoma cellular composition. Here, we wished to improve insights into liposarcoma cellular hierarchy. Tumor...
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