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Article

Human placental lactogen transcriptional enhancer. Tissue specificity and binding with specific proteins.

The Journal of biological chemistry - 5 Aug 1990

Walker W H, Fitzpatrick S L, Saunders G F

Abstract excerpt

Human placental lactogen (hPL) and growth hormone (hGH) are thought to be derived from a common ancestral gene and have similar nucleotide and amino acid sequences. Although the genes are similar in structure, they are expressed in different tissues. A transcriptional enhancer has been found 2.2 kilobases 3' of the hPL3 gene at the distal extreme of the hPL/hGH gene cluster. This enhancer is at least 20-fold more...

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PMID: 2376582

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TEF

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