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Article

The Human Placental Lactogen Genes: Structure, Function, Evolution and Transcriptional Regulation

1 Nov 1991

Abstract excerpt

hPL is a member of an evolutionarily related gene family including hGH and hPRL. Expression of hPL is limited to the placenta but its physiological actions are far reaching. hPL has a direct somatotropic effect on fetal tissues, it alters maternal carbohydrate and lipid metabolism to provide for fetal nutrient requirements, and aids in stimulation of mammary cell proliferation. Two hPL genes (hPL3 and hPL4)...

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Identifiers

PMID: 1760991
DOI: 10.1210/edrv-12-4-316

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