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Article

Germline PTEN mutation Cowden syndrome: an underappreciated form of hereditary kidney cancer.

The Journal of urology - 1 Dec 2013

Shuch Brian, Ricketts Christopher J, Vocke Cathy D, Komiya Takefumi, Middelton Lindsay A, Kauffman Eric C, Merino Maria J, Metwalli Adam R, Dennis Phillip, Linehan W Marston

Abstract excerpt

PURPOSE: Cowden syndrome is a hereditary cancer syndrome associated with a germline mutation in PTEN. Patients are predisposed to multiple malignancies including renal cell carcinoma. MATERIALS AND METHODS: Patients with Cowden syndrome were evaluated as part of a clinical protocol. Those with a...

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Share to Carcinoma, Renal Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23764071
DOI: 10.1016/j.juro.2013.06.012
PMCID: PMC4193347

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23764071-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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