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Article

Random fluctuation of selection coefficients and the extent of nucleotide variation in human populations.

Proceedings of the National Academy of Sciences of the United States of America - 25 Jun 2013

Miura Sayaka, Zhang Zhenguo, Nei Masatoshi

Abstract excerpt

It is well known that the selection coefficient of a mutant allele varies from generation to generation, and the effect of this factor on genetic variation has been studied by many theoreticians. However, no consensus has been reached. One group of investigators believes that fluctuating selection has an effect of enhancing genetic variation, whereas the other group contends that it has a diversity-reducing...

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Identifiers

PMID: 23754436
DOI: 10.1073/pnas.1308462110
PMCID: PMC3696816

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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