Article
Lentiviral-mediated gene transfer of siRNAs for the treatment of Huntington's disease.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013
Cambon Karine, Déglon Nicole
Abstract excerpt
This chapter describes the potential use of viral-mediated gene transfer in the central nervous system for the silencing of gene expression using RNA interference in the context of Huntington's disease (HD). Protocols provided here describe the design of small interfering RNAs, their encoding in...
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