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Article

Sustained effects of nonallele-specific Huntingtin silencing.

Annals of neurology - 1 Mar 2009

Drouet Valérie, Perrin Valérie, Hassig Raymonde, Dufour Noëlle, Auregan Gwennaelle, Alves Sandro, Bonvento Gilles, Brouillet Emmanuel, Luthi-Carter Ruth, Hantraye Philippe, Déglon Nicole

Abstract excerpt

OBJECTIVE: Huntington's disease (HD) is a fatal autosomal dominant neurodegenerative disorder caused by a polyglutamine expansion in the huntingtin (htt) protein. No cure is available to date to alleviate neurodegeneration. Recent studies have demonstrated that RNA interference represents a promi...

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Identifiers

PMID: 19334076
DOI: 10.1002/ana.21569

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19334076-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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