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Development of a High Density Hemagglutinin Protein Microarray to Determine the Breadth of Influenza Antibody Responses

1 Jun 2013

Abstract excerpt

We have developed an influenza hemagglutinin protein microarray to assess humoral recognition of diverse influenza strains induced by vaccination and infection. Each array consists of controls and 127 hemagglutinin antigens from 60 viruses, spotted in replicates to generate a single array of 1296 spots. Six arrays are configured on a single slide, which in the following analysis was probed simultaneously with 2...

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PMID: 23750544
DOI: 10.2144/000114041

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