Article
Interaction of plectin with keratins 5 and 14: dependence on several plectin domains and keratin quaternary structure.
The Journal of investigative dermatology - 1 Nov 2014
Bouameur Jamal-Eddine, Favre Bertrand, Fontao Lionel, Lingasamy Prakash, Begré Nadja, Borradori Luca
Abstract excerpt
Plectin, a cytolinker of the plakin family, anchors the intermediate filament (IF) network formed by keratins 5 and 14 (K5/K14) to hemidesmosomes, junctional adhesion complexes in basal keratinocytes. Genetic alterations of these proteins cause epidermolysis bullosa simplex (EBS) characterized by...
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