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Article

Interaction of plectin with keratins 5 and 14: dependence on several plectin domains and keratin quaternary structure.

The Journal of investigative dermatology - 1 Nov 2014

Bouameur Jamal-Eddine, Favre Bertrand, Fontao Lionel, Lingasamy Prakash, Begré Nadja, Borradori Luca

Abstract excerpt

Plectin, a cytolinker of the plakin family, anchors the intermediate filament (IF) network formed by keratins 5 and 14 (K5/K14) to hemidesmosomes, junctional adhesion complexes in basal keratinocytes. Genetic alterations of these proteins cause epidermolysis bullosa simplex (EBS) characterized by disturbed cytoarchitecture and cell fragility. The mechanisms through which mutations located after the documented...

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Identifiers

PMID: 24940650
DOI: 10.1038/jid.2014.255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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