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Environmental Epigenetics and Its Implication on Disease Risk and Health Outcomes

1 Dec 2012

Abstract excerpt

This review focuses on how environmental factors through epigenetics modify disease risk and health outcomes. Major epigenetic events, such as histone modifications, DNA methylation, and microRNA expression, are described. The function of dose, duration, composition, and window of exposure in remodeling the individual's epigenetic terrain and disease susceptibility are addressed. The ideas of lifelong editing of...

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PMID: 23744968
DOI: 10.1093/ilar.53.3-4.289

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