Article
Environmental epigenetics and asthma: current concepts and call for studies.
American journal of respiratory and critical care medicine - 15 Mar 2008
Miller Rachel L, Ho Shuk-Mei
Abstract excerpt
Recent studies suggest that epigenetic regulation (heritable changes in gene expression that occur in the absence of alterations in DNA sequences) may in part mediate the complex gene-by-environment interactions that can lead to asthma. The variable natural history of asthma (i.e., incidence and remission of symptoms) may be a result of epigenetic changes, such as DNA methylation, covalent histone modifications,...
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