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Article

Association of vitamin D serum levels and its common genetic determinants, with severity of liver fibrosis in genotype 1 chronic hepatitis C patients.

Journal of viral hepatitis - 1 Jul 2013

Petta S, Grimaudo S, Marco V D, Scazzone C, Macaluso F S, Cammà C, Cabibi D, Pipitone R, Craxì A

Abstract excerpt

Lower 25-hydroxyvitamin D [25(OH)D] serum levels have been associated with the severity of liver fibrosis in genotype 1 chronic hepatitis C patients (G1CHC). In addition, a recent genome-wide study identified genetic variants (rs12785878, near dehydrocholesterol reductase, DHCR7; rs10741657, near CYP2R1; and rs7041, near vitamin D-binding protein, GC) affecting 25(OH)D serum levels in healthy populations. We...

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Share to Cholestanetriol 26-Monooxygenase
Share to Chromatography, High Pressure Liquid
Share to Cytochrome P450 Family 2
Share to Liver Cirrhosis
Share to Oxidoreductases Acting on CH-CH Group Donors
Share to Serum
Share to Vitamin D
Share to Vitamin D-Binding Protein

Source

Identifiers

PMID: 23730842
DOI: 10.1111/jvh.12072

Genes

DHCR7

Provenance

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