Article
Identification and functional analysis of the primary pantothenate transporter, PfPAT, of the human malaria parasite Plasmodium falciparum.
The Journal of biological chemistry - 12 Jul 2013
Augagneur Yoann, Jaubert Lise, Schiavoni Matthieu, Pachikara Niseema, Garg Aprajita, Usmani-Brown Sahar, Wesolowski Donna, Zeller Skye, Ghosal Abhisek, Cornillot Emmanuel, Said Hamid M, Kumar Priti, Altman Sidney, Ben Mamoun Choukri
Abstract excerpt
The human malaria parasite Plasmodium falciparum is absolutely dependent on the acquisition of host pantothenate for its development within human erythrocytes. Although the biochemical properties of this transport have been characterized, the molecular identity of the parasite-encoded pantothenate transporter remains unknown. Here we report the identification and functional characterization of the first protozoan...
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