Article
Impact of family history of cancer on the incidence of mutation in epidermal growth factor receptor gene in non-small cell lung cancer patients.
Lung cancer (Amsterdam, Netherlands) - 1 Aug 2013
He Yayi, Li Shuai, Ren Shengxiang, Cai Weijing, Li Xuefei, Zhao Chao, Li Jiayu, Chen Xiaoxia, Gao Guanghui, Li Wei, Zhou Fei, Zhou Caicun
Abstract excerpt
BACKGROUND: Epidermal growth factor receptor (EGFR) activating mutation is an important predictive biomarker of EGFR tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC), while family history of cancer also plays an important role in the neoplasia of lung cancer. This study aimed to investigate the association between family history of cancer and EGFR mutation status in NSCLC population....
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