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Article

Perianal disease combined with NOD2 genotype predicts need for IBD-related surgery in Crohn's disease patients from a population-based cohort.

Journal of clinical gastroenterology - 1 Mar 2013

Nasir Bushra Farah, Griffiths Lyn, Nasir Aslam, Roberts Rebecca, Barclay Murray, Gearry Richard, Lea Rodney A

Abstract excerpt

BACKGROUND: Patients with Crohn's disease (CD) often require surgery at some stage of disease course. Prediction of CD outcome is influenced by clinical, environmental, serological, and genetic factors (eg, NOD2). Being able to identify CD patients at high risk of surgical intervention should assist clinicians to decide whether or not to prescribe early aggressive treatment with immunomodulators. METHODS: We...

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Source

Identifiers

PMID: 22739221
DOI: 10.1097/MCG.0b013e318258314d

Genes

NOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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