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SOX2 Expression and Prognostic Significance in Ovarian Carcinoma

30 May 2013

Abstract excerpt

The transcription factor SOX2 has been extensively studied for its role in embryonic stem cell self-renewal and pluripotency. More recent data suggest oncogenic functions of SOX2 and demonstrate expression in several carcinoma types, predominantly of squamous cell origin. The gene SOX2 is located at chromosome 3q26, a region that is frequently amplified in ovarian high-grade serous carcinoma. In this study, we...

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Share to Ovarian cancer diagnosis and treatment
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PMID: 23722508
DOI: 10.1097/pgp.0b013e31826a642b

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