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Article

SOX2 identified as a target gene for the amplification at 3q26 that is frequently detected in esophageal squamous cell carcinoma.

Cancer genetics and cytogenetics - 15 Oct 2010

Gen Yasuyuki, Yasui Kohichiroh, Zen Yoh, Zen Keika, Dohi Osamu, Endo Mio, Tsuji Kazuhiro, Wakabayashi Naoki, Itoh Yoshito, Naito Yuji, Taniwaki Masafumi, Nakanuma Yasuni, Okanoue Takeshi, Yoshikawa Toshikazu

Abstract excerpt

SOX2 is a transcription factor with a high-mobility group DNA-binding domain that functions as a master regulator during embryogenesis and organogenesis. We investigated DNA copy number aberrations in esophageal squamous cell carcinoma (ESCC) cell lines using a high-density oligonucleotide microarray and found frequent amplification at the chromosomal region 3q26. The estimated extent of the minimal overlapping...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20875870
DOI: 10.1016/j.cancergencyto.2010.01.023

Genes

SOX2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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