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Human Embryonic Stem Cell Lines Model Experimental Human Cytomegalovirus Latency

29 May 2013

Abstract excerpt

ABSTRACT Herpesviruses are highly successful pathogens that persist for the lifetime of their hosts primarily because of their ability to establish and maintain latent infections from which the virus is capable of productively reactivating. Human cytomegalovirus (HCMV), a betaherpesvirus, establishes latency in CD34 + hematopoietic progenitor cells during natural infections in the body. Experimental infection of...

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PMID: 23716573
DOI: 10.1128/mbio.00298-13

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