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Lgr proteins in epithelial stem cell biology

29 May 2013

Abstract excerpt

The ultimate success of global efforts to exploit adult stem cells for regenerative medicine will depend heavily on the availability of robust, highly selective stem cell surface markers that facilitate the isolation of stem cells from human tissues. Any subsequent expansion or manipulation of isolated stem cells will also require an intimate knowledge of the mechanisms that regulate these cells, to ensure...

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PMID: 23715542
DOI: 10.1242/dev.083113

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