Article
Hemolytic disease of the newborn due to anti-Jra from a Chinese mother with one novel and one classic heterozygous mutation.
Transfusion medicine (Oxford, England) - 1 Aug 2023
Xiao Jie, Yang Qixiu, Gao Shouxi, Song Hui, Zhao Fengyong, Guo Zhonghui, Zhang Yuyu, Zhu Ziyan, Ye Luyi, Xiang Dong
Abstract excerpt
OBJECTIVE: Investigation of a Jr(a-) family samples, identification of the mutant and assessment of the differences of Jr antigen density of the Jr(a-) family members, random adult and newborn individuals' RBCs. BACKGROUND: The anti-Jra antibody is generated when a Jr(a-) individual pregnant or transfused with Jr(a+) blood unit, which can lead to mild-to-moderate hemolytic disease of the foetus and newborn (HDFN)...
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