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Article

MicroRNA-21 promotes the proliferation and inhibits apoptosis in Eca109 via activating ERK1/2/MAPK pathway.

Molecular and cellular biochemistry - 1 Sept 2013

Liu Fengxia, Zheng Shutao, Liu Tao, Liu Qing, Liang Meng, Li Xiuling, Sheyhidin Ilyar, Lu Xiaomei, Liu Wenya

Abstract excerpt

The aim of this study was to investigate how miR-21 promotes proliferation and inhibits apoptosis in esophageal squamous cell carcinoma (ESCC). MTT, wound healing assay and cell cycle showed that proliferation and migration of ESCC cell line Eca109 cells were increased in miR-21 mimics group, and decreased in anti-miR-21 Oligonucleotide (AMO) group after transfection into Eca109 cells with miR-21 mimics, AMO and...

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PMID: 23709326
DOI: 10.1007/s11010-013-1693-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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