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Article

The involvement of mitochondrial amidoxime reducing components 1 and 2 and mitochondrial cytochrome b5 in N-reductive metabolism in human cells.

The Journal of biological chemistry - 12 Jul 2013

Plitzko Birte, Ott Gudrun, Reichmann Debora, Henderson Colin J, Wolf C Roland, Mendel Ralf, Bittner Florian, Clement Bernd, Havemeyer Antje

Abstract excerpt

The mitochondrial amidoxime reducing component mARC is a recently discovered molybdenum enzyme in mammals. mARC is not active as a standalone protein, but together with the electron transport proteins NADH-cytochrome b5 reductase (CYB5R) and cytochrome b5 (CYB5), it catalyzes the reduction of N-hydroxylated compounds such as amidoximes. The mARC-containing enzyme system is therefore considered to be responsible...

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Identifiers

PMID: 23703616
DOI: 10.1074/jbc.M113.474916
PMCID: PMC3711290

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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