Article
The nucleoprotein of severe fever with thrombocytopenia syndrome virus processes a stable hexameric ring to facilitate RNA encapsidation.
Protein & cell - 1 Jun 2013
Zhou Honggang, Sun Yuna, Wang Ying, Liu Min, Liu Chao, Wang Wenming, Liu Xiang, Li Le, Deng Fei, Wang Hualin, Guo Yu, Lou Zhiyong
Abstract excerpt
Severe fever with thrombocytopenia syndrome virus (SFTSV), a member of the Phlebovirus genus from the Bunyaviridae family endemic to China, is the causative agent of life-threatening severe fever with thrombocytopenia syndrome (SFTS), which features high fever and hemorrhage. Similar to other negative-sense RNA viruses, SFTSV encodes a nucleocapsid protein (NP) that is essential for viral replication. NP...
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