Article
The absence of a microbiota enhances TSLP expression in mice with defective skin barrier but does not affect the severity of their allergic inflammation.
The Journal of investigative dermatology - 1 Dec 2013
Yockey Laura J, Demehri Shadmehr, Turkoz Mustafa, Turkoz Ahu, Ahern Philip P, Jassim Omar, Manivasagam Sindhu, Kearney John F, Gordon Jeffrey I, Kopan Raphael
Abstract excerpt
Evidence is accumulating to suggest that our indigenous microbial communities (microbiota) may have a role in modulating allergic and immune disorders of the skin. To examine the link between the microbiota and atopic dermatitis (AD), we examined a mouse model of defective cutaneous barrier funct...
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