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Article

Comprehensive analysis of phenotypes and transcriptome characteristics reveal the best atopic dermatitis mouse model induced by MC903.

Journal of dermatological science - 1 Jun 2024

Zhang Shan, Fang Xiaokai, Xu Beilei, Zhou Yuan, Li Fang, Gao Yuwen, Luo Yang, Yao Xu, Liu Xiaochun

Abstract excerpt

BACKGROUND: Although several mouse models of exogenous-agent-induced atopic dermatitis (AD) are currently available, the lack of certainty regarding their similarity with human AD has limited their scientific value. Thus, comprehensive evaluation of the characteristics of mouse models and their similarity with human AD is essential. OBJECTIVE: To compare six different exogenous-agent-induced AD mouse models and...

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PMID: 38806322
DOI: 10.1016/j.jdermsci.2024.05.003

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