Article
Discrepancies of HIV-1 reverse transcriptase resistance interpretation of insertions and deletions between two genotypic algorithms.
Intervirology - 1 Jan 2013
López-Lopes Giselle Ibette Silva, Lança André Minhoto, de Paula Ferreira João Leandro, Souza Luciana Oliveira, de Macedo Brígido Luís Fernando
Abstract excerpt
BACKGROUND: Bioinformatics algorithms have been developed for the interpretation of resistance from sequence submission, which supports clinical decision making. This study evaluated divergences of the interpretation of the genotyping in two commonly used algorithms, using sequences with indels of reverse transcriptase genes. METHODS: Sequences were obtained from virus RNA of patients failing highly active...
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