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Article

Melanoma inhibitory activity promotes melanoma development through activation of YBX1.

Pigment cell & melanoma research - 1 Sept 2013

Schmid Rainer, Meyer Katharina, Spang Rainer, Schittek Birgit, Bosserhoff Anja-Katrin

Abstract excerpt

Melanoma inhibitory activity (MIA), a small soluble secreted protein, is functionally important for progression of malignant melanoma. We recently revealed that p54(nrb) acts as a mediator of MIA action. In this study, we characterize the transcriptional regulation of p54(nrb) by MIA to explain MIA's molecular action. We identified one highly conserved region in the p54(nrb) promoter that is necessary and...

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Source

Identifiers

PMID: 23672612
DOI: 10.1111/pcmr.12119

Genes

MIA
YBX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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