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Article

Ammonium transport proteins with changes in one of the conserved pore histidines have different performance in ammonia and methylamine conduction.

PloS one - 1 Jan 2013

Wang Jinan, Fulford Tim, Shao Qiang, Javelle Arnaud, Yang Huaiyu, Zhu Weiliang, Merrick Mike

Abstract excerpt

Two conserved histidine residues are located near the mid-point of the conduction channel of ammonium transport proteins. The role of these histidines in ammonia and methylamine transport was evaluated by using a combination of in vivo studies, molecular dynamics (MD) simulation, and potential of mean force (PMF) calculations. Our in vivo results showed that a single change of either of the conserved histidines...

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Identifiers

PMID: 23667517
DOI: 10.1371/journal.pone.0062745
PMCID: PMC3647058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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