Article
Phenotypic heterogeneity of hereditary gynecologic cancers: a report from the Creighton hereditary cancer registry.
Familial cancer - 1 Dec 2013
Casey Murray Joseph, Bewtra Chhanda, Lynch Henry T, Snyder Carrie, Stacy Mark, Watson Patrice
Abstract excerpt
To determine the validity of observations suggesting a significant dichotomy of gynecologic cancers determined by linkage to specific genetic defects associated with two major autosomal dominant hereditary cancer syndromes; the Creighton University Hereditary Cancer Registry was searched for female carriers of germ line mutations in BRCA1 and BRCA2, associated with the Hereditary Breast Ovarian Cancer syndrome,...
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