Article
Comparative pan-genomics and in vivo validation identify genetic factors important for virulence of Salmonella enterica serovar Gallinarum and serovar Enteritidis in the avian host.
Microbiological research - 1 May 2026
Fei Xiao, Moussa Jennifer, Guerra Priscila Regina, Nisar Sajid, Ma Yibing, Wang Weizhe, Saraiva Mauro M S, Li Heng, Zhou Zhemin, Olsen John Elmerdahl
Abstract excerpt
Salmonella enterica subspecies enterica serovar Gallinarum biovar Gallinarum (SGa) and Pullorum (SPu) are avian-specific pathogens causing systemic disease, while S. Enteritidis (SEnt) is a broad host range serovar causing gastroenteritis. The genomic mechanisms underlying this difference in host range and pathogenicity remain incompletely understood. Here, we performed a large-scale pan-genome analysis of 5440...
Topics
- Animals
- Chickens
- Virulence
- Salmonella Infections, Animal
- Salmonella enterica
- Poultry Diseases
- Genome, Bacterial
- Genomics
- Serogroup
- Salmonella enteritidis
- Host Specificity
- Prophages
- Bacterial Proteins