Article
Whole-genome, deep pyrosequencing analysis of a duck influenza A virus evolution in swine cells.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Aug 2013
Bourret Vincent, Croville Guillaume, Mariette Jérôme, Klopp Christophe, Bouchez Olivier, Tiley Laurence, Guérin Jean-Luc
Abstract excerpt
We studied the sub-population level evolution of a duck influenza A virus isolate during passage in swine tracheal cells. The complete genomes of the A/mallard/Netherlands/10-Nmkt/1999 strain and its swine cell-passaged descendent were analysed by 454 pyrosequencing with coverage depth ranging from several hundred to several thousand reads at any point. This allowed characterization of defined minority...
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