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Article

Role of IL28-B polymorphisms in the treatment of chronic hepatitis B HBeAg-negative patients with peginterferon.

Antiviral research - 1 Feb 2014

Boglione Lucio, Cusato Jessica, Allegra Sarah, Esposito Isabella, Patti Francesca, Cariti Giuseppe, Di Perri Giovanni, D'Avolio Antonio

Abstract excerpt

Interleukin (IL)28-B polymorphism has been related to interferon response in the treatment of hepatitis C, but its role in chronic hepatitis B (CHB) therapy is still poorly understood. We aimed to investigate the effect of IL28-B polymorphisms in the treatment with pegylated-interferon (PEG-IFN) of patients with CHB. We retrospectively analyzed 190 patients with chronic hepatitis B e antigen (HBeAg) negative,...

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Identifiers

PMID: 24316030
DOI: 10.1016/j.antiviral.2013.11.014

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