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Article

Cell-extrinsic effects of the tumor unfolded protein response on myeloid cells and T cells.

Annals of the New York Academy of Sciences - 1 May 2013

Zanetti Maurizio

Abstract excerpt

Tumor-infiltrating myeloid cells, macrophages, and dendritic cells (DCs) are key regulators of tumor immunity and growth. The origin of tumor-derived signals that instruct myeloid cells in the tumor microenvironment is only partially understood. The endoplasmic reticulum (ER) stress response, or unfolded protein response (UPR), provides survival advantages to tumor growth. However, the cell-extrinsic effects of...

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PMID: 23651187
DOI: 10.1111/nyas.12103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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