Article
The plant cyclin-dependent kinase inhibitor ICK1 has distinct functional domains for in vivo kinase inhibition, protein instability and nuclear localization.
The Plant journal : for cell and molecular biology - 1 Aug 2003
Zhou Yongming, Li Genyi, Brandizzi Federica, Fowke Larry C, Wang Hong
Abstract excerpt
Interactor/inhibitor 1 of Cdc2 kinase (ICK1) from Arabidopsis thaliana is the first plant cyclin-dependent kinase (CDK) inhibitor, and overexpression of ICK1 inhibits CDK activity, cell division and plant growth in transgenic plants. In this study, ICK1 and deletion mutants were expressed either...
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