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Optimization of human corneal endothelial cell culture: density dependency of successful cultures in vitro

3 May 2013

Abstract excerpt

BACKGROUND: Global shortage of donor corneas greatly restricts the numbers of corneal transplantations performed yearly. Limited ex vivo expansion of primary human corneal endothelial cells is possible, and a considerable clinical interest exists for development of tissue-engineered constructs using cultivated corneal endothelial cells. The objective of this study was to investigate the density-dependent growth...

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PMID: 23641909
DOI: 10.1186/1756-0500-6-176

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