Article
Genetic background of idiopathic pulmonary fibrosis.
Expert review of molecular diagnostics - 1 May 2013
Santangelo Simona, Scarlata Simone, Zito Anna, Chiurco Domenica, Pedone Claudio, Incalzi Raffaele Antonelli
Abstract excerpt
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease characterized by progressive fibrosing interstitial pneumonia. The histological pattern, which displays dense fibrosis with active areas of fibroblastic proliferation, suggests a pathogenetic role of aberrant response to healing of multiple microscopic, repeated alveolar epithelial injuries. Although the exact etiology of the disease is...
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