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Network News: The Replication of Kinetoplast DNA

20 Sept 2012

Abstract excerpt

One of the most fascinating and unusual features of trypanosomatids, parasites that cause disease in many tropical countries, is their mitochondrial DNA. This genome, known as kinetoplast DNA (kDNA), is organized as a single, massive DNA network formed of interlocked DNA rings. In this review, we discuss recent studies on kDNA structure and replication, emphasizing recent developments on replication enzymes, how...

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PMID: 22994497
DOI: 10.1146/annurev-micro-092611-150057

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