Article
[Mutation analysis of the HBV reverse transcriptase in nucleos(t)ide-treated patients with chronic HBV infection].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Dec 2012
Jiao Xiu-Juan, Peng Xun, Jiao Xiu-Min, Wang Jin-Sheng, Sun Xie-Wen, Zhao Pei-Li, Wang Shou-Yun, Liu Jia-Qun, Li Tong, Yang Jing-Xian
Abstract excerpt
OBJECTIVE: To characterize genotypic resistance within HBV RT region in chronic hepatitis B (CHB) patients with nucleos(t)ide analogue (NA) treatment. METHODS: Serum samples of 229 CHB patients with NA treatment were obtained. Full-length HBV RT sequences were amplified, sequenced and analyzed, on the following NA resistant (NAr) mutations belonging to different NAr pathways. RESULTS: Among 229 HBV isolates,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
