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Article

Old and new prognostic factors in acute myeloid leukemia with deranged core-binding factor beta.

American journal of hematology - 1 Jul 2013

Cairoli Roberto, Beghini Alessandro, Turrini Mauro, Bertani Giambattista, Nadali Gianpaolo, Rodeghiero Francesco, Castagnola Carlo, Lazzaroni Francesca, Nichelatti Michele, Ferrara Felicetto, Pizzolo Giovanni, Pogliani Enrico, Rossi Giuseppe, Martinelli Giovanni, Morra Enrica

Abstract excerpt

Acute myeloid leukemia (AML) with deranged core-binding factor beta (CBFβ) is usually associated with a favorable prognosis with 50-70% of patients cured using contemporary treatments. We analyzed the prognostic significance of clinical features on 58 patients with CBFβ-AML aged ≤60 years. Increasing age was the only predictor for survival (P <0.001), with an optimal cut-point at 43 years. White blood cells...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23619823
DOI: 10.1002/ajh.23461

Genes

KIT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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