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Article

Cytochrome P450 2B6 and 2C9 genotype polymorphism--a possible cause of prasugrel low responsiveness.

Thrombosis and haemostasis - 1 Jul 2013

Franken Cora C, Kaiser Andreas F C, Krüger Jan C, Overbeck Kristina, Mügge Andreas, Neubauer Horst

Abstract excerpt

The cytochrome P450 (CYP) isoenzymes are essential for the metabolic activation of the prodrug prasugrel. Little is known about the impact of polymorphism of these isoenzymes on the prevalence of prasugrel low responsiveness (PLR) in patients with coronary artery disease. We investigated the freq...

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Identifiers

PMID: 23615745
DOI: 10.1160/TH13-01-0021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23615745-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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