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Article

Receptor binding by a ferret-transmissible H5 avian influenza virus.

Nature - 16 May 2013

Xiong Xiaoli, Coombs Peter J, Martin Stephen R, Liu Junfeng, Xiao Haixia, McCauley John W, Locher Kathrin, Walker Philip A, Collins Patrick J, Kawaoka Yoshihiro, Skehel John J, Gamblin Steven J

Abstract excerpt

Cell-surface-receptor binding by influenza viruses is a key determinant of their transmissibility, both from avian and animal species to humans as well as from human to human. Highly pathogenic avian H5N1 viruses that are a threat to public health have been observed to acquire affinity for human receptors, and transmissible-mutant-selection experiments have identified a virus that is transmissible in ferrets, the...

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Identifiers

PMID: 23615615
DOI: 10.1038/nature12144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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