Article
Associations between APOE genotypes and disease susceptibility, joint damage and lipid levels in patients with rheumatoid arthritis.
PloS one - 1 Jan 2013
Maehlen Marthe T, Provan Sella A, de Rooy Diederik P C, van der Helm-van Mil Annette H M, Krabben Annemarie, Saxne Tore, Lindqvist Elisabet, Semb Anne Grete, Uhlig Till, van der Heijde Désirée, Mero Inger Lise, Olsen Inge C, Kvien Tore K, Lie Benedicte A
Abstract excerpt
OBJECTIVE: Apolipoprotein E (APOE) genotypes are associated with cardiovascular disease (CVD) and lipid levels. In rheumatoid arthritis (RA), an association has been found with disease activity. We examined the associations between APOE genotypes and disease susceptibility and markers of disease severity in RA, including radiographic joint damage, inflammatory markers, lipid levels and cardiovascular markers....
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