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Article

Investigation of possible epistatic interactions between GRIA2 and GRIA4 variants on clinical outcomes in patients with major depressive disorder.

The Journal of international medical research - 1 Jun 2013

Chiesa Alberto, Lia Loredana, Lia Claudia, Lee Soo-Jung, Han Changsu, Patkar Ashwin A, Pae Chi-Un, Serretti Alessandro

Abstract excerpt

OBJECTIVES: To investigate the effects of glutamate receptor, ionotropic, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) 2 (GRIA2) rs4260586 and glutamate receptor, ionotropic, AMPA 4 (GRIA4) rs10736648 single nucleotide polymorphisms (SNPs) on response to antidepressants in Korean patients with major depressive disorder (MDD), and to ascertain whether epistatic interactions might exist between...

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Source

Identifiers

PMID: 23613500
DOI: 10.1177/0300060513477295

Genes

GRIA2
GRIA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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