Article
Bradykinin receptor gene variant and human physical performance.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Mar 2004
Williams Alun G, Dhamrait Sukhbir S, Wootton Peter T E, Day Stephen H, Hawe Emma, Payne John R, Myerson Saul G, World Michael, Budgett Richard, Humphries Steve E, Montgomery Hugh E
Abstract excerpt
Accumulating evidence suggests that athletic performance is strongly influenced by genetic variation. One such locus of influence is the gene for angiotensin-I converting enzyme (ACE), which exhibits a common variant [ACE insertion (I)/deletion (D)]. ACE can drive formation of vasoconstrictor ANG II but preferentially degrades vasodilator bradykinin. The ACE I allele is associated with higher kinin activity. A...
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